和傅克反应有关的问题我知道在苯环上有强致钝基团的时候,不能发生傅克烷基化反应我现在想知道 苯环上有一个-Cl基 该反应能

比如生成的三氯化苄也会和没反应的苯发生 付克反应,得到二氯二苯基甲烷 查看更多答案

The Friedel-Crafts reactions are a set of reactions developed by Charles Friedel and James Crafts in 1877.There are two main types of Friedel-Crafts reactions:alkylation reactions and acylation reactions.This reaction type is part of electrophilic aromatic substitution.
A:Friedel-Crafts alkylation involves the alkylation of an aromatic ring and an alkyl halide using a strong Lewis acid catalyst.With anhydrous ferric chloride as a catalyst,the alkyl group attaches at the former site of the chloride ion.
B:Friedel-Crafts acylation is the acylation of aromatic rings with an acyl chloride using a strong Lewis acid catalyst.Friedel-Crafts acylation is also possible with acid anhydrides.Reaction conditions are similar to the Friedel-Crafts alkylation.This reaction has several advantages over the alkylation reaction.Due to the electron-withdrawing effect of the carbonyl group,the ketone product is always less reactive than the original molecule,so multiple acylations do not occur.Also,there are no carbocation rearrangements,as the carbonium ion is stabilized by a resonance structure in which the positive charge is on the oxygen.

傅克反应.先理解成：指的是通过AlCl3催化,将卤代烃接到苯环上,主要生成物是甲苯和氯化氢.此外还有可能继续取代,生成其他产物.
具体的.http://blog.163.com/lssqq@126/blog/static/11159926720091076350419/
或者自行百度也行.
注：本人是渣渣,化学吧里有很多大神,自行去提问,额.

钝化基团是说明反应不容易进行 不能说明不能 条件适当 可以反应

比如
生成的三氯化苄也会和没反应的苯发生 付克反应,得到二氯二苯基甲烷

催化活性活动顺序大致如下：AlCl3>FeCl3>SbCl3
三氯化铝是效力最强,也是最常用的,
但催化剂的活性常因反应物和反应条件的改变而发生变化,
效力最强的催化剂并不一定在所有情况下都是最合适的催化剂,
操作者应根据被取代氢的活性、烷基化试剂的类别和反应条件来选择合适的催化剂.

一般用硝基苯作溶剂,因为硝基是强钝化基团,不会发生付克反应.
苯一般过量,2：1左右,为了防止付克反应生成多烷基化产物,实际上没有制备意义.

付克烷基化：烷基是致活基团,苯环连上烷基以后比原来更容易和第二个卤代烷反应,所以不容易控制,应用也少.
付克酰基化：酰基致钝,所以酰基苯很难再上第二个酰基,反应容易控制,所以应用较多.
此外,烷基化可能有碳正离子重排,比如氯丙烷和苯在AlCl3作用下得到的是异丙苯.而酰基化没有重排,所以副反应也少.