validation是什么意思

英语翻译
1.INTRODUCTION
The aim of this validation study has been to demonstrate that the method AD-TM-R165335-F051-POW-LD-000959-v2 is suitable for determination of the particle size distribution of R165335 – F051 by means of laser diffraction.The following compounds have been used in the validation.
2.METHOD VALIDATION
2.1.Precision
2.1.1.Analysis Repeatability – test results and acceptance
criteria
Analysis repeatability expresses the precision of the analytical method under the same operating conditions over a short interval of time.The repeatability of the method has been determined by the 6-fold analysis of 1 sample of the drug product batch by 1 analyst on 1 day,using 1 instrument.Based on the
volume distribution,for each analysis the dV10,dV50 and dV90 cumulative undersizes are reported.In addition,for each series of particle size data the averages,standard deviations,relative standard deviations (RSD),and 95% confidence intervals are reported.For evaluation purposes,the RSD values are compared with the acceptance criteria.
2.1.2.Intermediate Precision – test results and acceptance
criteria
Intermediate precision expresses the within laboratory variations,e.g.different days,different analysts,etc.For this purpose,the intermediate precision of the method has been determined by 2 analysts,each analysing the product in 6-fold.The analyses have been done using 1 instrument,whereas analyst 1 performed a 6-fold analysis on day 1,and analyst 2 performed a 6-fold analysis on day 2.The validation data as obtained for the
analysis repeatability testing will be used as the analyst 1 data set.Based on the volume distribution,for each analysis the dV10,dV50 and dV90 cumulative undersizes are reported.In addition,for each series of particle size data the averages,standard deviations,relative standard deviations (RSD),and 95% confidence intervals are reported.For evaluation purposes,the RSD values are compared with the acceptance criteria.
Participating Analysts:
• Analyst 1:Global Analytical Development,Method Development,Beers (Belgium)
• Analyst 2:Global Analytical Development,Stability Evaluation and Release,Beers (Belgium)
2.1.3.Conclusions
The particle size method AD-TM-R165335-F051-POW-LD-000959-v2 has
been demonstrated to show an adequate analysis repeatability and
intermediate precision.
2.2.Robustness
The robustness of the analytical method has been tested during the method development and is a measure of its capacity to remain unaffected by small but deliberate variations in method parameters.The capability of method AD-TM-R165335-F051-LD-000959-v2 to remain unaffected has been tested by varying the following parameter:
1.Slid Width (and thereby the mass flow of the product in the instrument)
2.2.1.Conclusions
The robustness of the method has been demonstrated by showing the validity of the method after small deliberate changes to the slid width.

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英语翻译
co-investment by a trusted partner is a validation by a third-*** of the enterprise’s possibility

英语翻译
Mixed-method validation of pedagogical concepts for an intercultural online learning environment
混合的方法验证的教学概念间的在线学习环境
回答者：jgxz12 - 秀才 三级 12-7 19:54
你以为我不会google语言工具来随便弄一下？

英语翻译
Description:Request Validation has detected a potentially dangerous client input value,and processing of the request has been aborted.This value may indicate an attempt to compromise the security of your application,such as a cross-site scripting attack.You can disable request validation by setting validateRequest=false in the Page directive or in the configuration section.However,it is strongly recommended that your application explicitly check all inputs in this case.

英语翻译
Here,we report on the optimisation and validation of a liquid chromatographic method for the determination of 12 biologically active amines from
vegetal food products in a single 40-min run.The suitability of the method was checked in five vegetal products of distinct matrix:spinach (leaves),
hazelnut (high protein and fat content),banana,potato (high starch content),and milk chocolate (processed).Sample preparation consisted of a
0.6M perchloric acid extraction from a minced homogeneous aliquot.For samples with high starch content,a previous mild hydrolytic treatment
was required to prevent gel formation.The range of linearity was from 0.1 to 10 mg/l,except for serotonin and spermine (from 0.5 to 10 mg/l),
and the correlation coefficient was higher than 0.997 (P < 0.001) for all standard curves.The detection limits and the determination limit were
below 0.07 and 0.2 mg/l,respectively,except for spermine,which was 0.14 and 0.4 mg/l.The precision of the method was satisfactory; the relative
standard deviation obtained for each amine in each product was acceptable according to Horwitz.Recovery was between 77 and 110% for all
amines,irrespective of the product.