acquaint yourself with something:to deliberately find out ab

After we are acquaint with each other,he confided to me that his dream is to be engaged in the greatest things which human beings are capable of.

acquaint 使了解(to make famliar)
释义：
1.acquaint是正式用词,基本意思是“让某人获知”,指向某人介绍某事的经过或传递有关全过程的信息,使其知晓.
2 .acquaint是及物动词,以“告知”的对象为间接宾语(名词、人称代词或反身代词),而直接宾语即告知的内容则由with引起的介词短语或名词性从句充当.
3.acquaint的过去分词acquainted常用作形容词,用于系表结构中,强调熟悉或知晓的状态.
回答你的问题：
1.acquaint onself with sth 使某人了解某事
You must acquaint yourself with your new job.
你必须熟悉你的新工作.
He acquaints himself with the training of the units.他经常了解部队的训练情况.
2.此词用于被动语态中,过去分词acquainted已经失去动作意义,相当于一个形容词.
例如:“我是去年认识他的.”不能译作:I acquainted him last year.或 I was acquainted with him last year.第一句是语态错误,第二句混淆了“状态”和“动作”,只能译成:I got [became] acquainted with him last year.或 I made his acquaintance last year.

acquaint sb with 是使...熟悉...
句子是说他完全熟悉了自己新的职责.让自己熟悉职责.

把我的计划告知他.
I acquaint him with my plans.（主动式）
My plans are acquainted with him.（被动式）
acquaint是及物动词,后面接的是名词人或物或代词,所以acquaint sb with sth,是固定用法,就如把它给我give it to me中give也是做及物动词用的,而不是你说的acquaint接了with而造成及物动词接介词的矛盾.只不过是将它被动化后with就紧跟在后面了

口语里面哪里见过acquaint.老外可能说I want to meet/know your XXX.

acquaint 有 使了解、熟悉 的意思 当然在介绍人或物的时候 和introduce是一样的
至于区别
Let me acquaint you with the facts.
让我把事实告诉你.
My mother acquainted her with my intention.
我母亲把我的意图告诉了她.
I am already acquainted with him.
我已经和他相熟.
You must acquaint yourself with your new duties.
你必须熟悉你的新任务.
看了这几个句子你应该懂了

我是在熟人的一个网站上得到的你的地址,所以我决定写邮件给你,我想认识你,我是很认真的想和你认识,如果你能给我回信我会非常开心.

狠抱歉，我在网上查出来的讲解，延伸的太多，甚至有拉丁语的解释，这些对学生而言没多大必要，不如研究别的前缀。高考必备上说:有at,to之意，或表示加强意义，牛津词典甚至没把它列为前缀，我看了几十个有ac的词，意思繁杂凌乱无法总结，再查查吧...