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Smells Like Teen Spirit 歌词

2023-07-25 13:19:02
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歌曲名:Smells Like Teen Spirit
歌手:Nirvana
专辑:From The Muddy Banks Of The Wishkah

Nirvana
Smells Like Teen Spirit
Load up on guns and Bring your friends
It"s fun to lose And to pretend
She"s over bored And self assured
Oh no, I know A dirty word
hello, how low? (x bunch of times)
With the lights out it"s less dangerous
Here we are now Entertain us
I feel stupid and contagious
Here we are now Entertain us
A mulatto An albino
A mosquito My Libido
Yeah
I"m worse at what I do best
And for this gift I feel blessed
Our little group has always been
And always will until the end
hello, how low? (x bunch of times)
With the lights out it"s less dangerous
Here we are now Entertain us
I feel stupid and contagious
Here we are now Entertain us
A mulatto An albino
A mosquito My Libido
Yeah
And I forget Just why I taste
Oh yeah, I guess it makes me smile
I found it hard It was hard to find
Oh well, whatever, nevermind
hello, how low? (x bunch of times)
With the lights out it"s less dangerous
Here we are now Entertain us
I feel stupid and contagious
Here we are now Entertain us
A mulatto An albino
A mosquito My Libido
Yeah, a denial
A denial
A denial...

http://music.b***.com/song/7550698

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contagious是什么意思

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infectious 和 contagious

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2023-07-24 22:25:122

The government warned the people of being careful about this kind of contagious disease.

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2023-07-24 22:25:191

“微笑会传染”这句话用英语应该怎么说?

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谁能解释下面英文的意思?

http://www.iciba.com/ 1,抗衡2 contempuous三考虑4遏制5传染性6完善7领事8诠释9 consrict10惊愕
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一首英文歌 白话翻译过来差不多是 爱家瓦的手 乌拉一味的谁为谁手

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2023-07-24 22:28:081

英语翻译 14

 它成为了很明确的一点是,传染性打哈欠与同理心。但是为什么呢?也许最好的解释我们为什么打哈欠,以及为什么打哈欠是传染的,可以发现在酒吧在大草原上几万年前。  一些科学家认为,打哈欠是一种无意识的应对压力的情况下:当我们打哈欠,我们增加的血液流向大脑,从而使我们更加警惕。呵欠传染的可能是一种安静的沟通,我们的祖先散布消息说一头饥饿的狮子在附近。恐惧是一种情感,我们会同情、打哈欠可以作为一个线索,我们恐惧的蔓延。
2023-07-24 22:28:163

contagious是什么意思

contagious 英[ku0259nu02c8teu026adu0292u0259s]美[ku0259nu02c8tedu0292u0259s]adj. 有传染性的; 传染病的; 有感染力的; 会蔓延的;全部释义>>[例句]Sometimes people can be contagious without even having symptoms.有时人们甚至没有任何症状就开始传染病毒了。
2023-07-24 22:28:431

contagious的中英文歌词

ContagiousUh oh Uh ohWhen you"re around但你在我周围I don"t know what to do我不知所措I do not think that I can wait我迫不及待To go over and to talk to you想重温你,和你交谈I do not know what I should say我不知道应该说什么So I walk out in silence于是我在安静中走开That"s when I start to realize这是我开始意识到的时候What you bring to my life你给我的生活带来了什么Damn this guy can make me cry这个可恶的家伙使我哭泣It"s so contagious太具有感染力了I cannot get it out of my mind我不能停止想你It"s so outrageous太惊人了You make me feel so high all the time你永远使我觉得兴奋They all say that you"re no good for me他们都说爱上你对我没有好处But I"m too close to turn around但我已不能自拔I"ll show them they don"t know anything我会让他们知道他们一无所知I think I"ve got you figured out我认为我会让你被理解So I walk out in silence于是我在安静中走开That"s when I start to realize这是我开始意识到的时候What you bring to my life你给我的生活带来了什么Damn this guy can make me smile这个可恶的家伙使我微笑It"s so contagious太具有感染力了I cannot get it out of my mind我不能停止想你It"s so outrageous太惊人了You make me feel so high你使我觉得兴奋I will give you everything我会给你我的一切I will treat you right我会好好对待你If you just give me a chance如果你给我一个机会I can prove I"m right我会证明我是适合你的It"s so contagious太具有感染力了I cannot get it out of my mind我不能停止想你It"s so outrageous太惊人了You make me feel so high你使我觉得兴奋All the time永远
2023-07-24 22:29:071

anthem的《Contagious》 歌词

歌曲名:Contagious歌手:anthem专辑:HERALDIC DEVICE[by:赖润诫「Contagious」作词∶Naoto ShibataVICP-64961作曲∶Naoto Shibata歌∶ANTHEMHey! 无敌のbright man 话を闻いてくれよ役には立たないだろうが话を闻いてくれよ bright manOh, may be fairy talesFor you, must be meaninglessまわりの谁もがみんな自分を叹いて生きてる同时に谁もがみんな自分を蹴り上げ这い回るOh, the one and only wayYes! だからもがくのさOh, until we get to the place sometimeIt"s Contagious. No refuse. Never die. Never die.Do you think that we are foolish men 止まれないのさThe Contagious. It"s taking me to the end. To the end.Do you feel it"s a foolish game?何かがまた駆り立てるのさWe are sailing, we are sailingToward the light that we neededWe are calling, we are callingTo the place that we want to stayOh, maybe fairy talesYes! だからもがくのさFor you, must be meaninglessOh, the one and only wayYes! 今日も もがくのさOh, until we get to the place sometimeIt"s Contagious. No refuse. Never die. Never dieDo you think that we are foolish men 止まれないのさThe Contagious. It"s taking me to the end. To the endDo you feel it"s a foolish game?何かがまた駆り立てるのさNo refuse, no refuseNever die, never diehttp://music.baidu.com/song/14452143
2023-07-24 22:29:201

So Contagious 歌词

歌曲名:So Contagious歌手:acceptance专辑:PhantomsSo ContagiousAcceptancePhantomsartis-Acceptancesong-So ContagiousOh no, this couldn"t be more unexpectedAnd I can tell that I"ve been moving in so slowDon"t let it throw you off too farCause I"ll be running right behind youCould this be out of line? (Could this be out of line?)To say you"re the only one breaking me down like thisYou"re the only one I would take a shot onKeep me hanging on so contagiouslyOohhh, when I"m around you I"m predictableCause I believe in loving you at first sightI know it"s crazy but I"m hoping to..To take a hold of youCould this be out of line? (Could this be out of line?)To say you"re the only one breaking me down like thisYou"re the only one I would take a shot onKeep me hanging on so contagiouslyOh you"re everything I"m wantingCome to think of it, I"m achingOn account of my transgression..Will you welcome this confession?Could this be out of line? (Could this be out of line?)To say you"re the only one breaking me down like thisYou"re the only one I would take a shot onKeep me hanging on so contagiouslyCould this be out of line? (Could this be out of line?)To say you"re the only one breaking me down like thisYou"re the only one I would take a shot onKeep me hanging on so contagiouslyhttp://music.baidu.com/song/24880945
2023-07-24 22:29:271

Smells Like Teen Spirit 歌词

歌曲名:Smells Like Teen Spirit歌手:Nirvana专辑:SinglesNirvanaSmells Like Teen SpiritLoad up on guns and Bring your friendsIt"s fun to lose And to pretendShe"s over bored And self assuredOh no, I know A dirty wordhello, how low? (x bunch of times)With the lights out it"s less dangerousHere we are now Entertain usI feel stupid and contagiousHere we are now Entertain usA mulatto An albinoA mosquito My LibidoYeahI"m worse at what I do bestAnd for this gift I feel blessedOur little group has always beenAnd always will until the endhello, how low? (x bunch of times)With the lights out it"s less dangerousHere we are now Entertain usI feel stupid and contagiousHere we are now Entertain usA mulatto An albinoA mosquito My LibidoYeahAnd I forget Just why I tasteOh yeah, I guess it makes me smileI found it hard It was hard to findOh well, whatever, nevermindhello, how low? (x bunch of times)With the lights out it"s less dangerousHere we are now Entertain usI feel stupid and contagiousHere we are now Entertain usA mulatto An albinoA mosquito My LibidoYeah, a denialA denialA denial...http://music.baidu.com/song/55068937
2023-07-24 22:29:471

Céline Dion的《Us》 歌词

歌曲名:Us歌手:Céline Dion专辑:Original Album ClassicsRegina Spektor - Us"Story of a boy and a girl"They made a statue of usAnd it put it on a mountain topNow tourists come and stare at usBlow bubbles with their gumTake photographs for fun, for funThey"ll name a city after usAnd later say it"s all our faultThen they"ll give us a talking toThen they"ll give us a talking toBecause they"ve got years of experienceWe"re living in a den of thievesRummaging for answers in the pagesWe"re living in a den of thievesAnd it"s contagiousAnd it"s contagiousAnd it"s contagiousAnd it"s contagiousWe wear our scarves just like a nooseBut not "cause we want eternal sleepAnd though our parts are slightly usedNew ones are slave labor you can keepWe"re living in a den of thievesRummaging for answers in the pagesWe"re living in a den of thievesAnd it"s contagiousAnd it"s contagiousAnd it"s contagiousAnd it"s contagiousThey made a statue of usThey made a statue of usThe tourists come and stare at usThe sculptor"s marble sends regardsThey made a statue of usThey made a statue of usOur noses have begun to rustWe"re living in a den of thievesRummaging for answers in the pagesWere living in a den of thievesAnd it"s contagiousAnd it"s contagiousAnd it"s contagiousAnd it"s contagiousAnd it"s contagiousAnd it"s contagiousAnd it"s contagiousAnd it"s contagiousFor the movie 《500 days of summer》http://music.baidu.com/song/7432168
2023-07-24 22:29:561

Smells Like Teen Spirit 歌词

歌曲名:Smells Like Teen Spirit歌手:The Flying Pickets专辑:The Original Flying Pickets Vol. One「Smells Like Teen Spirit」作词∶Krist Novoselic作曲∶Krist Novoselic歌∶MiChiLoad up on guns and Bring your friendsIt"s fun to lose And to pretendShe"s over bored And self assuredOh no, I know A dirty wordhello, hello, hello, how low?hello, hello, hello, how low?hello, hello, hello, how low?hello, hello, hello.With the lights out it"s less dangerousHere we are now Entertain usI feel stupid and contagiousHere we are now Entertain usA mulatto An albino A mosquito My LibidoYay, yay, yayI"m worse at what I do bestAnd for this gift I feel blessedOur little group has always beenAnd always will until the endhello, hello, hello, how low?hello, hello, hello, how low?hello, hello, hello, how low?hello, hello, hello.With the lights out it"s less dangerousHere we are now Entertain usI feel stupid and contagiousHere we are now Entertain usA mulatto An albino A mosquito My LibidoYay, yay, yayAnd I forget Just why I tasteOh yeah, I guess it makes me smileI found it hard It was hard to findOh well, whatever, nevermindhello, hello, hello, how low?hello, hello, hello, how low?hello, hello, hello, how low?hello, hello, hello.With the lights out it"s less dangerousHere we are now Entertain usI feel stupid and contagiousHere we are now Entertain usA mulatto An albino A mosquito My Libidoa denial A denial A denial...収録:KiSS KiSS xxx発売日:2009/05/27http://music.baidu.com/song/1045778
2023-07-24 22:30:031

传染是动词吗?

2023-07-24 22:30:202

求艾薇儿好听畅销的英文歌(歌名中英文都要写)

Too much too askyou were mineinnocencehotcontagiousbomb astic lovetake me away我觉得这些都挺不错的,好的也还有很多,你慢慢就会发现的…
2023-07-24 22:30:465

来源: https://learningenglish.voanews.comLaughing is one of life"s most simple pleasures. It is free. You can do it anywhere. And it makes you feel good! 笑是生活中最简单的乐趣之一。笑不受约束,不受地域限制,还能让你心情舒畅! There is another thing you should know about laughter: Laughter is contagious. 你还应该了解笑的另一个特点:笑具有感染力。 Like the flu, laughter can spread easily among people. Often when we hear someone laughing in a crowded room or a packed train, for example, we start laughing too — even if we have no idea why. 像流感一样,笑声很容易在人与人之间弥漫。例如,我们在拥挤的房间或火车上听到有人大笑时,不知为何我们也会跟着大笑。 But unlike the flu, even a good handwashing will not protect you against breaking into a fit of laughter. Your eyes water, your heart rate goes up and your face gets that beautiful laughter glow. 但与流感不同的是,洗手洗得再仔细也无法让你遏制笑的冲动。你的眼睛笑得盈满泪水,心跳加快,脸上也笑出美丽的红晕。In fact, many doctors say that mental health can affect physical health. You might even say, "Laughter is the best medicine." 实际上,许多医生都说心理健康会影响生理健康。你甚至可以说:“笑是最佳良药。” However, "laughter is the best medicine" does not mean that you should not take medicine when you are sick. It simply means that having a positive outlook might help ease your troubles. 但是,“笑是最佳良药” 并不意味着你生病时可以不吃药。这句话只是在说,积极的心态可能会减轻你的痛苦。 People who use this expression are probably pretty happy people. 会说这句话的人,大多是快乐的人。 Then there are those other types — you know, people who are always grumpy. 你知道的,有的人爱发脾气。 We could call someone who does not like to laugh a curmudgeon. A curmudgeon is bad-tempered, ill-natured and just generally not fun to be around. 我们称某些不喜欢笑的人为急性子。他们脾气暴躁,性格不善,与之相处大抵不会有趣。 Well, unless you yourself are a curmudgeon. If that is the case, you two could hang out and not laugh and not have fun together! You know what we say — misery loves company. 好吧,除非你就是急性子。若真是这样,你可以和另一个急性子一起出去玩,一起板着脸,一起不开心。你懂的——痛苦需要陪伴。 As we also like to say: Laugh and the world laughs with you; cry and you cry alone. 我们还想说:笑时,世界跟你一起笑,哭时,你只能独自垂泪。
2023-07-24 22:31:001

英语作文

How to protect from the H1N1 Flu In recent days,the H1N1 Flu has spread throu the whole world and has caused so many cases that brought about a great deal of panic.H1N1 mainly can be infected via the unprotected contact with H1N1 patients or the infected environment.It is appreaing that people who contact may be hot,coughing,and has a sore throat,a headache,severely may even to be cold as well as vomit,and eventually to death. In order to prevent it happens,infecting vaccine and having a healthy and clean habbit is of great significance.It is not a serious matter that we can cant"s master,to believe is to be brave!
2023-07-24 22:31:383

taking是什么意思?

1. 拿,取,获得[U]2. 捕获物,捕获量[C]3. 进款,收入[P]4. 【主英】【古】激动,不安a.1. 动人的,迷人的2. 【口】(疾病)传染性的加-S; takings: 进款,收入take的进行时 taking.
2023-07-24 22:32:052

Chester see everything中文歌词

Chester see everything中文歌词她爱我,离开了我她仍然保持我想要更多,但感觉是空的她必须去吗?我会知道吗?爱与离开我她欺骗我她吻的方式如此误导我以为她会留下来然后她就走了在我关闭你的名字的章节之前有一对夫妇的东西,我从来没有说你的眼睛是美妙的你的微笑太你的笑是会传染的你的心是真的你的触摸有美丽你的吻是爱你是每一个梦想的人的一切你是我的一切这让我坠入爱河已经有一段时间了但我仍然发现我在与我们的最后的再见我以为这份爱会持续现在我生活在过去因为这只是我和我的心的回忆将跳过一个节拍当你靠近的时候现在你从来没有在这里在我找到力量之前让这个去有一对夫妇的东西我需要你知道你的眼睛是美妙的你的微笑太你的笑是会传染的你的心是真的你的触摸有美丽你的吻是爱你是每一个梦想的人的一切你是我的一切这让我坠入爱河你的眼睛是美妙的你的微笑太你的笑是会传染的你的心是真的是的,你的触摸有美丽你的吻是爱你是我的一切是的你是我的一切你是我的一切这让我坠入爱河是的,在爱中Chester see everything英文歌词She loved and left meStill she kept meWanting more, but feelings emptyDid she have to go?Will I ever know?Love and leave meShe decieved meThe way she kissedWas so misleadingI thought that she might stayThen she went awayBefore I close the chapter to your nameThere"s a couple things I never got to sayYour eyes are wonderfulYour smile is tooYour laugh"s contagiousAnd your heart is trueThere"s beauty in your touchAnd your kiss is loveYou"re everything that every guy dreams ofYou"re everythingThat makes meFall in loveIt"s been some timeBut still I findI"m struggling with ourLast goodbyeI thought this love would lastNow I"m living in the pastCause it"s just meAnd memories of how my heartWould skip a beatWhenever you were nearNow you"re never hereBefore I find the strengthTo let this goThere"s a couple thingsI need for you to knowYour eyes are wonderfulYour smile is tooYour laugh"s contagiousAnd your heart is trueThere"s beauty in your touchAnd your kiss is loveYou"re everything that every guy dreams ofYou"re everythingThat makes meFall in loveYour eyes are wonderfulYour smile is tooYour laugh"s contagiousAnd your heart is trueYEAH, there"s beauty in your touchAnd your KISS is loveYou"re everythingYesYou"re everythingYou"re everythingThat makes meFall in loveYeah, in love
2023-07-24 22:32:211

求Little Boots的remedy的歌词以及中文翻译!!

去百度MP3里输入Little Boots就可以了,那里有歌词,最前面的人已经把它翻译了。。。
2023-07-24 22:32:514

出彩中国人2015初赛大结局插曲英文歌曲

Smells Like Teen Spirit - NirvanaLoad up on guns把枪上膛and Bring your friends带上狐朋狗友It s fun to lose多好玩去迷失And to pretend去假装She s over bored她行为极端And self assured并且自傲无比Oh no I know哦,不!我不由得想到A dirty word一个肮字hello hello你好 你好hello how low你好怎样低点hello hello你好 你好hello how low你好怎样低点hello hello你好 你好hello how low你好怎样低点hello hello你好 你好hello how low你好怎样低点With the lights out当灯光熄灭it s less dangerous危险少些Here we are now我们在这里Entertain us来给我们一个乐子I feel stupid我感觉有点愚蠢and contagious却感染所有人Here we are now我们在这里Entertain us娱乐我们A mulatto一位黑白混血An albino一个白化病人A mosquito一只蚊子My Libido还有我的性冲动,Yeah耶~I m worse at what我天生有毁掉I do best我一技之长的事情And for this gift对这个天赋I feel blessed还感觉良好Our little group我们的小团体has always been将永远存在And always will并且不朽until the end直到永远hello hello你好 你好hello how low你好怎样低点hello hello你好 你好hello how low你好怎样低点hello hello你好 你好hello how low你好怎样低点hello hello你好 你好hello how low你好怎样低点With the lights out当灯光熄灭it s less dangerous危险少些Here we are now我们在这里Entertain us来给我们一个乐子I feel stupid娱乐我们and contagious却感染所有人Here we are now我们在这里Entertain us来给我们一个乐子A mulatto一位黑白混血An albino一个白化病人A mosquito一只蚊子My Libido还有我的性冲动,Yeah耶~And I forget然后我忘了Just why I taste为什么我尝它?Oh yeah I guess哦,我猜it makes me smile它会让我微笑吧I found it hard这问题太难It was hard to find找不到答案Oh well whatever喔,好吧,无所谓了,nevermind管他呢hello hello你好 你好hello how low你好怎样低点hello hello你好 你好hello how low你好怎样低点hello hello你好 你好hello how low你好怎样低点hello hello你好 你好hello how low你好怎样低点With the lights out当灯光熄灭it s less dangerous危险少些Here we are now我们在这里Entertain us来给我们一个乐子I feel stupid我感觉挺蠢?and contagious却感染所有人Here we are now我们在这里Entertain us来给我们一个乐子A mulatto一位黑白混血An albino一个白化病人A mosquito一只蚊子My Libido还有我的性冲动,A denial逃避A denial逃避A denial逃避A denial逃避A denial逃避A denial逃避A denial逃避A denial逃避A denial逃避
2023-07-24 22:33:101

Catching Feelings 歌词

歌曲名:Catching Feelings歌手:Justin Bieber专辑:BelieveCatching FeelingsJustin BieberSwing comes up on another morningMy mind never wakes up with that you wantedAnd it"s crazy to me, I even see you in my dreamsIs this meant to be? could this happening to meWe were best of friends since we were this highSo why do I get nervous every time you walk byWe would be on the phone all dayNow I can"t find the words to say to youNow what i"m supposed to doCould there be a possibilityI"m trying to say what"s upCause i"m made for you, and you for meBaby now is time for rightsTry to keep it all togetherBut enough is enoughThey say we"re too young for loveBut i"m catching feelings, catching feelingsIn my head we"re already togetherI"m cool alone, but with you i"m betterI just wanna see you smileYou say the word and i"ll be right thereI ain"t never going nowehreI"m just trying to see where this can take usCause everything about you girl is so contagiousI think I finally got it doneNow it"s left to do now, it"s get at the mirrorAnd say it to herCould there be a possibilityI"m trying to say what"s upCause i"m made for you, and you for meBaby now is time for rightsTry to keep it all togetherBut enough is enoughThey say we"re too young for loveBut i"m catching feelings, catching feelingsShould I tell her, how I really feelOr should I moving closer just be stillHow would I know?Cause if I take a chance, and I touch her handWell everything changesHow do I know, if she feels the same?Could there be a possibilityI"m trying to say what"s upCause i"m made for you, and you for meBaby now is time for rightsTry to keep it all togetherBut enough is enoughThey say we"re too young for loveBut i"m catching feelings, catching feelingshttp://music.baidu.com/song/14890044
2023-07-24 22:33:181

纽约不插电的歌词和译文

The Man Who Sold The World - David Bowie   《出卖世界的人》       We passed upon the stair   我们在天堂阶梯的两边(评价自己一生)      We spoke of was and when   谈论着过去的岁月与往事      Although I wasn"t there   虽然我与他已不在同一世界      He said I was his friend   他却说他曾是我的朋友      Which came as some surprise   对我来说多么震惊      I spoke into his eyes   于是我凝视着他说      I thought you died alone   “我以为你已经死去      A long long time ago   在很久很久以前就已经孤独死去了”      Oh no, not me   哦,不,那不是我      I never lost control   我从未失去控制      You"re face to face   与你面对面的      With The Man Who Sold The World   是这个出卖世界的人      I laughed and shook his hand   于是我笑着握他的手      And made my way back home   并踏上回乡的旅途      I searched for form and land   我寻找我的家园和归宿      For years and years I roamed   我多年流浪四方      I gazed a gazely stare at all the millions here   我凝视数百万闪烁的星光      We must have died alone,   我们早该孤独地逝去了      A long long time ago   在很久很久以前就孤独地逝去      Who knows? not me   谁知道呢?反正不是我      We never lost control   我们从未失去控制      You"re face to face   与你面对面的      With the Man who Sold the World   是这个出卖世界的人
2023-07-24 22:33:282

sickness,illness,disease,trouble的区别?

恶心 病态 疾病 困境
2023-07-24 22:33:594

becontraryto例句有哪些

becontraryto的例句是:Businessesofcoursecan"tactuallyinvestinthelottery-thatwouldbecontrarytothetermsoftheirloan-buttheycandosimilarthings.当然了,企业是不能拿贷款去买彩票的,这会有悖于贷款的合同条款,但他们可能会去做类似的事。It"snotroubleatall;onthecontrary,itwillbeagreatpleasuretohelpyou.这根本不麻烦。相反,我很乐意帮助你。Unemploymentseemstoberising,despiterepeatedassurancestothecontrary.尽管反复担保减少失业,失业率看来却在上升。becontraryto的例句是:Businessesofcoursecan"tactuallyinvestinthelottery-thatwouldbecontrarytothetermsoftheirloan-buttheycandosimilarthings.当然了,企业是不能拿贷款去买彩票的,这会有悖于贷款的合同条款,但他们可能会去做类似的事。It"snotroubleatall;onthecontrary,itwillbeagreatpleasuretohelpyou.这根本不麻烦。相反,我很乐意帮助你。Unemploymentseemstoberising,despiterepeatedassurancestothecontrary.尽管反复担保减少失业,失业率看来却在上升。becontraryto的网络解释是与.....相反:+ing的词组|becontraryto与相反|objectto反对。becontraryto的意思是违反;与相反。一、网络解释点此查看becontraryto的详细内容1.与.....相反:+ing的词组|becontraryto与相反|objectto反对2.becontraryto在线翻译2.违反;反对:becommonto对某人来说很普通,|becontraryto违反;反对,|bedevotedto致力,3.违反:becontagious传染|becontraryto违反|becontrarytothefact违背事实4.becontraryto的反义词4.和...相反,违反:beblindto看不见,对...视而不见|becontraryto和...相反,违反|7.形容词+with二、例句Businessesofcoursecan"tactuallyinvestinthelottery-thatwouldbecontrarytothetermsoftheirloan-buttheycandosimilarthings.当然了,企业是不能拿贷款去买彩票的,这会有悖于贷款的合同条款,但他们可能会去做类似的事。It"snotroubleatall;onthecontrary,itwillbeagreatpleasuretohelpyou.这根本不麻烦。相反,我很乐意帮助你。Unemploymentseemstoberising,despiterepeatedassurancestothecontrary.尽管反复担保减少失业,失业率看来却在上升。becontraryto的相关临近词be、Bechin点此查看更多关于becontraryto的详细信息
2023-07-24 22:34:091

sickness和disease的区别

用于医学上表示各种病称时,通常用 disease。如:contagious diseases 传染病 English disease 气管炎heart disease 心脏病 lung disease 肺病a nervous disease 神经病 a sex disease 性病skin disease 皮肤病注:有个别搭配也用 illness。如:mental illness [sickness] 精神病 disease 表示“疾病”,通常指具体的“疾病”(可数)。如:Most diseases could be wiped out. 多数疾病是可以消灭的。I caught the disease from you. 这病我是从你那传染来的。It was a horrible disease. 这是一种可怕的疾病。Arthritis is a chronic disease. 关节炎是一种慢性病。Measles, mumps and influenza are common diseases. 麻疹、腮腺炎和流感是常见病。注:有时指疾病的总称(不可数),即通称的“疾病”。如:Rats spread disease. 老鼠传染疾病。Cleanliness helps prevent disease. 清洁有助于预防疾病。Disease is usually caused by germs. 疾病多由病菌引起。Many antibiotic drugs ore used to combat disease. 许多抗生素药品用来和疾病作斗争。2. sickness ,它们主要用于表示生病的时间或因病(disease)导致的不健康状态等。如:He can"t come because of sickness. 他因病不能来。He died after a long sickness. 他死之前病了很久。She is cheerful in spite of her sickness. 她尽管有病,但还是快乐。He was weak from a long sickness. 由于长期生病他身体很虚弱。Tell me a little about your sickness. 给我谈谈你的病。Chicken pox is a common childhood sickness. 水痘是儿童时期的常见病。Do you know what his sickness is? 你知道他患什么病吗?另外,sickness还可表示“呕吐”“恶心”。如:He"s suffering from sickness and diarrhoea. 他上吐下泻。He felt a wave of sickness come over him. 他感到一阵恶心。
2023-07-24 22:34:191

高二英语上册必修五知识点:Living with disease

【 #高二# 导语】直面高二的挑战,认清高二的自己,明确高二的目标,意义重大。因为,高二的这个岔路口,分出的是渐行渐远的两条路,指向的是人生意义上的两个截然相反的阶段性终端。 高二频道为正在奋斗的你整理了《高二英语上册必修五知识点:Living with disease》希望你喜欢! Ⅰ.Hot words and hot phrases常用词与常用词组 1.Medical studies show that AIDS virus cannot be transmitted via the following routes:cups,glasses,toilet seats,swimming pools,mosquitoes,other insects or blood donation.(P.49) 2.AIDS is a disease that breaks down the body"s immune system and leaves a person defenceless against infections and illness.(P.51) 3.People get AIDS after having been infected with the HIV virus.(P.51) 4.People transmit HIV by having unprotected sex,by receiving infected blood transfusions or,as in Xiaohua"s case,through birth.(P.51) 5.Xiaohua"s mother contracted the HIV virus when she was 28,and she died of AIDS only three years after Xiaohua was born.(P.51) 6.The disease is spreading faster in Africa and parts of Asia,mainly because of a lack of proper health care,prevention and education.(P.51) 7.The drugs that are available are much too expensive and difficult to find.(P.51) 8....but she does not let that knowledge discourage her.(P.51) 9.She also goes to visit other AIDS patients in hospitals across the country to support them and cheer them up.(P.51) 10.The disease is not the only thing that AIDS patients have to suffer from.(P.52) 11....that can persuade hospitals and companies to allocate more funds for AIDS research and education.(P.52) 12.Xiaohua has learnt to live with HIV and the fact she will eventually get AIDS.(P.52) 13.Two years ago,Dr Richards had asked me a great many questions and had taken samples of my blood.(P.55) 14.Mum held my hand and I saw that she was weeping.(P.55) 15.Cancer is a disease that begins in cells.(P.55) 16.In my body,the production of cells is disrupted.(P.55) 17.Doctors do know that cancer is not caused by injury and is not contagious—it does not spread from one person to another.(P.55) 18.The cancer in my body has been defeated for the moment.(P.55) 19.Living with cancer has made me realize how precious life is and how important it is for us to take every chance to live life to the fullest.(P.55) 20.Every day is a new opportunity and I have learnt to appreciate every minute of each day. Ⅱ.Language points and grammar focus语言点和语法重点 A.Language points语言点 1.HIV/AIDS is incurable...(P.49) AIDS is a disease that...leaves a person defenceless against infections and illness.(P.51) 本单元中由前缀或后缀派生出的反义词的小结 2.People get AIDS after having been infected with the HIV virus.(P.51) 完成时的动名词的被动式的内涵及用法 3.As with most diseases and disasters,the young suffer the most. “定冠词 + 形容词/过去分词”表示“一类人”的用法的小结 4.I had been feeling sick for a long time and my mum had taken me to hospital to have me examined.(P.55) 1)过去完成进行时的内涵及用法 2)“to have + 宾语 + 过去分词”的两个内涵及用法 5.The treatment was successful and I was able to go home after exactly fourteen months,two days and six hours in hospital.(P.55) was/were able to do与could do在内涵上的区别及各自的用法 6.I have been living with cancer for two years and...(P.55) 现在完成进行时的内涵及用法 Ⅲ.Skills of the four essential abilities:listening,speaking,reading and writing听、说、读、写四项基本能力的学习技巧 1.Listening:Master the main idea of a long dialogue through the inner connections among the questions so as to have better understanding of the questioned details 从各设问间的内在联系把握较长对话的中心思想,更好理解各检测点的细节 2.Speaking:Talk about deadly diseases and attitudes towards AIDS,cancer,etc. 关于那些致命疾病及对待艾滋病、癌症等的态度的谈论 3.Reading:Make full use of informational words and phrases 充分利用信息词 4.Writing:How to write a personal narrative 如何写一篇个人经历过的叙述性故事 【同步练习题】 Ⅰ.课文练习 1.根据句意及提示,在空白处填入适合语境且语法正确的单词。 1)We have a________(十多岁的,青少年的)son. 2)A doctor can"t cure his own________.(疾病) 3)Many sick people have been saved because of________.(输血) 4)The TV________(电视公司)provides educational programs. 5)They are________(专家),but his specialism is omniscience. 2.单项填空。 1)Talk about ________diseases and attitudes towards AIDS,cancer,etc. A.death B.dying C.dead D.deadly 2)Some people got ________this strange disease and they died within a few months. A.infected with B.infected to C.immune to D.immune with 3)I have been there ________times. A.a great deal of B.a good deal of C.a great many D.a large amount of 4)I remember ________you about it once. A.to tell B.telling C.told D.tell 5)The book ________on the floor for ten minutes but no one has picked it up. A.is lying B.has lain C.has been lying D.lay 3.语法重点练习。 用括号中动词的虚拟语气的正确形式填空。 1)If I________(be)you,I would wear the overcoat. 2)If you________(leave)earlier,you would have caught the train. 3)If you had taken her advice,you________(not fail). 4)I wish I________(know)several foreign languages. 5)It was a lovely day yesterday,I wish I________(go)for an outing. 6)I suggest that he________(report)the matter to the police. Ⅰ. 1.1)teenager 根据此句的上下文及提示,应填teenager。 2)illness 根据句意及提示,应填illness。 3)transfusion 根据句意及提示,应填名词transfusion。 4)network 根据句意及提示,应填network。 5)specialists 根据句意及提示,应填名词复数。 2.1)D 根据句意及这四个词的区别,应选deadly(致命的)。 2)A 根据句意及infect的用法,应选infected with。 3)C 根据句意及这四个词的用法,A、B选项修饰不可数名词,D选项也修饰不可数名词,只有C选项修饰可数名词。 4)B 根据句意及remember to do sth.及remember doing sth.的用法,应选B。 5)C 此句应用现在完成进行时。 3.1)were 请查看Grammar focus部分(1)。 2)had left 请查看Grammar focus部分(1)。 3)would not have failed.请查看Grammar focus部分(1)。 4)knew 请查看Grammar focus部分(5)。 5)had gone 请查看Grammar focus部分(5)。 6)(should)report 请查看Grammar focus部分(6)。
2023-07-24 22:34:261

想知道更多给力的英文歌曲

toss it upselwyn - negative thingsRihanna - Only Girljls - privatepitbull - give me every thingkaty perry - last friday night
2023-07-24 22:34:344

玛瓦·柯林斯的名言

1 There is a brilliant child locked inside every student.在每一个学生的内在,都深藏着一颗闪闪发光的赤子之心。2 Don"t try to fix the students, fix ourselves first. The good teacher makes the poor student good and the good student superior. When our students fail, we, as teachers, too, have failed.不要试图改变学生,首先要改变自己。好老师使差学生成为好学生,好学生变得更出色。如果我们的学生失败了,作为教师的我们也同样失败了。3 The essence of teaching is to make learning contagious, to have one idea spark another.教的实质就是努力使学习的热情蔓延,并使彼此之间的灵感持续不断地相互激发。4 Once teachers try the Socratic, or direct method of teaching, they will never return to anything that cannot produce the "magic."一旦教师试图使用问答式或直接结论式的教学法,他们就再也没有可能回到任何可以产生“奇迹”的地方了。5 Success doesn"t come to you... you go to it.成功不是想来的...你只能走向成功。6 Excellence is not an act but a habit. The things you do the most are the things you will do best.卓越不是一个行为,而是一种习惯。你做的最出色的事都是你最愿意尽力做的事。7 Trust yourself. Think for yourself. Act for yourself. Speak for yourself. Be yourself. Imitation is suicide.相信自己,想你自己所想的,做你自己愿做的,说你自己要说的,做你自己。任何模仿都是自杀行为。8 Determination and perseverance move the world; thinking that others will do it for you is a sure way to fail.果断的决定和坚韧的意志可以改变世界,期待依赖什么人的帮助就能达到目标是绝对行不通的。9 Character is what you know you are, not what others think you have.自己是怎样的人自己最知道,管他别人怎么说呢。10 If you can"t make a mistake, you can"t make anything.一个人如果连犯错都不敢,他终将一事无成。11 Mr. Meant-to has a friend, his name is Didn"t-Do. Have you met them? They live together in a house called Never-Win. And I am told that it is haunted by the Ghost of Might-have-Been.“认命”先生有一位朋友,他的名字叫“别干”。你见过他们吗?他们俩一起住在一间被叫做“不成”的房子里。我听说这栋房子里游荡着一个叫做“没准”的鬼魂。
2023-07-24 22:34:521

esb webservice 和 htpp的区别

这个不太懂,你问问专业人士吧
2023-07-24 22:30:112

‘你多大年龄’用英语怎么说

How old are you?
2023-07-24 22:30:138

肺癌治疗的靶向药物?

  靶向治疗为肿瘤治疗带来了新的革命,将成为本世纪肿瘤治疗中最具潜力、最有希望的疗法。下面是我推荐给大家的,供大家参考。   一、EGFR突变   EGFR***英语:epidermal growth factor receptor,简称为EGFR、ErbB-1或HER1***是表皮生长因子受体***HER***家族成员之一。该家族包括HER1***erbB1,EGFR***、HER2***erbB2,NEU***、HER3***erbB3***及HER4***erbB4***。HER家族在细胞生理过程中发挥重要的调节作用。   EGFR基因在亚裔腺癌人群中的突变频率是10%-40%,常见突变位点:19外显子缺失突变,21外显子L858R点突变及18与20外显子突变等。   一代易瑞沙、特罗凯、凯美纳靶向的出世,创造了肺癌治疗史上的奇迹。后续抑制作用较强的二代不可逆抑制剂阿法替尼也进入大家视野,阿法替尼是靶向EGFR及HER2的双靶点抑制剂,疗效肯定,但国人的不良反应相对多些。而一代二代药物治疗在一年左右的时间会出现不同程度的耐药,在对于耐药机制的研究中发现了T790M的二次突变,针对于此的三代EGFR-TKI抑制剂AZD9291也因此普及,形成了目前三代EGR-TKI的治疗阶梯。我们也要认识到国内上市的靶向药物只有一代的易瑞沙,特罗凯,凯美纳,二代药物阿法替尼即将上市,三代药物也只有临床试验,基于药物未在中国上市,病情进展后可以进行化疗。   二、ALK融合或重排   ALK融合或重排在肺腺癌中占5%-10%,其常见的融合方式是EML4-ALK。其靶向的一代药物是国内已有的克唑替尼,可产生74%的有效率。而长期使用的患者也会在中位1-2年时间出现耐药,即发生ALK守门基因的突变导致继发耐药,从而促发了二代甚至是三代药物的出现,也形成了ALK治疗的三阶梯,但国内上市的ALK靶向药物只有克唑替尼一种,化疗仍是ALK耐药后的选择。   三、ROS1的融合   ROS1的融合在肺腺癌中突变率较低,1.2%--1.7%,常见于年轻、非吸菸、腺癌、高级别组织病理型别患者。这一基因融合与ALK类似,具有明确的肿瘤形成驱动性及较好的临床疗效。因此2017.2版NCCN指南中首次将ROS1提到肺腺癌的常规检测中,制定了该类患者特定的临床治疗路径。   对于ROS1重排阳性的患者,一线初试治疗推荐克唑替尼用药,有效率可达到72% ,耐药时间19.2 月,病情进展后可以进行化疗或PD-1的免疫治疗。   肺癌的免疫治疗   1、抗体靶向的免疫治疗在很多恶性肿瘤上已获得早期成功,在晚期肺癌和其它肿瘤的治疗中已经起到了很大的作用。   2、一些靶向PD-1受体的单克隆抗体***nivolumab, pembrolizumab*** 或其配体PD-L1 ***atezolizumab, durvalumab, avelumab***已应用于临床。这些药物的早期临床试验已证实在经治疗的晚期NSCLC患者中,14-20%表现出迅速且持久的反应,且生存率的改善显著。最主要的副作用是无力、疲劳、丧失食欲、恶心及腹泻。   3、抗PD-1或抗PD-L1药物的临床疗效及安全性被4个随机临床试验支援,其中有代表性的2个是在经基于铂类化疗治疗的患者中比较nivolumab与多西他赛治疗效果--CheckMate 017试验和CheckMate 057试验。   4、检查点抑制剂的获益主要限于PD-L1阳性肿瘤人群。Pembrolizumab在PD-L1表达细胞数≥50%的情况下,已被FDA批准作为二线及以上线的治疗。默克公司宣布一项达到终点的大型研究表明,在PD-L1表达细胞数≥50%的情况下,pembrolizumab与化疗相比,PFS和OS获益明显。在一项包含所有NSCLC组织学亚型的II期试验中,atezolizumab与多西他赛相比,表现出明显获益。   5、整体的资料表明PD-1抑制剂倾向于在经过标准化疗的肺鳞癌中作为二线治疗,在非肺鳞癌中至少需要满足PD-L1阳性的条件。   6、在之前未经治疗的患者中,抗PD-1或抗PD-L1抑制剂的早期试验的结果喜人--在PD-L1阳性患者中1年生存期超过70%。几项试验正在比较这些药物联合铂类治疗方案作为一线治疗的效果。   肺癌的症状   1、咯血   气管,支气管和肺组织出血,经口腔咯出称为咯血,咯血量的多少视病因或病变的性质而异。   2、呼吸异常   人呼吸频率成人为16~20次/min,与心脏搏动次数的比例为1:4。   3、痰有恶臭味   痰的气味呈恶臭味时,肺部炎症伴有厌氧菌感染。见于肺脓肿、支气管扩张及肺的恶性肿瘤晚期等肺部疾病。   4、鼠尾征   鼠尾征指支气管肺癌沿支气管的纵轴浸润蔓延,使支气管呈尾巴状狭窄且不规则的缺损。
2023-07-24 22:30:141

esb与ejb有可比性吗?区别是什麽?形象的解说一下

ESB 站在更高的位置,它的组成部件是 EJB,当一个请求进来,会按某个我们的查找到一个服务器去调用EJB,这些 EJB 都提供 web service 接口展示给服务器。
2023-07-24 22:30:202

古诗 望岳这古诗的解释

分类: 文化/艺术 解析: 《望岳》是中国古代诗歌中吟诵率较高的一首诗。大约在开元二十八年(740),杜甫二十九岁时,到兖州探望父亲后由齐入鲁,途经泰山,写下了这首诗。这是诗人仅存少数的早年作品之一。人们在品读此诗时,除了感受到泰山之雄伟外,恐怕更多的是被诗中那种“会当凌绝顶,一览众山小”的胸怀所激动、感染,因为这既是盛唐的时代精神的概括,又给人们留下很深的启示。 一、整体把握 这首诗是杜甫的早期作品。唐玄宗开元二十四年(736),年轻的诗人离开了长安,到兖州(今属山东省)去省亲——其父杜闲当时任兖州司马。此后大约三四年内,他一直在山东、河北一带漫游,结交了不少朋友。这首诗就是这期间写的。诗中热情地赞美了泰山高大雄伟的气势和神奇秀丽的景色,也透露了诗人早年的远大抱负,历来被誉为歌咏泰山的名篇。 全诗可分两大层,都是切着“望”字写的。 前两联为第一大层,着力写泰山的整体形象。“岱宗夫如何?齐鲁青未了”写远望所见。泰山位于古代齐、鲁两国之间,其北为齐,其南为鲁,齐、鲁之“青”,是泰山掩映的结果。“未了”,绵绵不尽之意。这里,诗人想说的是,你想知道泰山是个什么样子吗?请看,它那苍翠的山色掩映着辽阔无边的齐鲁大平原。这是借齐鲁两地来烘托泰山那拔地而起、参天耸立的形象。“造化钟神秀,阴阳割昏晓”,这是近望所见。上句写泰山的秀美,用的是虚笔。为什么要用虚笔?因为泰山的秀美实在是一言难尽,不如只写造物主对泰山情有独钟,这是诗人的强烈感受,是泰山的秀美在诗人心灵上的折光反映。下句写泰山的高大,这是实写。“阴阳”分指山的南、北两面,山南先得日光,故易晓;山北日光不到,在晓犹昏。“割”字炼得极好,从山的北面来看,那照临下土的阳光就像被一把硕大无朋的刀切断了一样,突出了泰山遮天蔽日的形象。 后两联为第二大层,也写了泰山景物,但着力表现的是诗人的感受。“荡胸生曾云,决眦入归鸟”,写的是实景,乃细望所见。泰山极高,白日里可以望见山腰间的团团云气,层出不穷;又极幽深,黄昏时可以望见归巢的鸟儿渐渐隐入山谷之中。诗人抓住这两个景物细节表达了心情的激荡和眼界的空阔,然后顺理成章地写出了他心底的愿望:“会当凌绝顶,一览众山小。”这是化用孔子的名言:“登泰山而小天下”。但用在这里却有深刻的含义:它不止是诗人要攀登泰山极顶的誓言,也是诗人要攀登人生顶峰的誓言。诗人早年就“窃比稷与契”(《自京赴奉先县咏怀五百字》),常以“致君尧舜上,再使风俗淳”(《奉赠韦左丞丈二十二韵》)自任,没有这样的情怀,是写不出如此动人的诗句的。 这首诗虽是八句四联,中间两联又都是对仗,但它不是律诗而是古体诗,它不讲究平仄,而且押的是仄声韵。 二、问题研究 《望岳》的艺术特色 杜甫曾到过泰山之巅,但没有为此写诗。这是三十年后他在《又上后园山脚》这首诗里提到的:“昔我游山东,忆戏东岳阳。穷秋立日观,矫首望八荒。”“日观”即日观峰,位于泰山之巅的东南方,是游人观日出的最佳处。以杜甫的才情,既已在此“矫首望八荒”,再写几首决非难事,可他为什么不写呢?我们无妨做点推测——用后人的眼光来看,这大概是因为《望岳》一首已经写尽了泰山的形神,充分展示了诗人胸中才情,确实不需要再写了。我们读这首诗,在领略泰山的高远幽深、神奇秀丽的同时,也仿佛看到了诗人那卓然独立的形象;特别是读到它的末联,更使人浮想联翩,仿佛跟诗人一道神游于泰山的绝顶之上,进一步感受到泰山的俯瞰群山的气概,对诗人青年时代兼济天下的远大抱负也就洞若观火了。正因为有如此深远的意境,这首诗历来被誉为咏泰山的绝唱。
2023-07-24 22:30:241

肺腺癌IV期能活多久?

最近又在门诊看了几个年轻的肺腺癌患者,都是女性,比较幸运的是都是早期肿瘤,不需要后续的治疗。近十年,肺癌的病理类型发生了很大的变化,与以前不同,如今肺腺癌占据发病率第一的位置,占所有肺癌人群的40-50%,早中期肺腺癌仍然是根治性手术治疗为主,而IV期肺癌病人一般没有手术治疗机会,治疗手段包括放化疗、靶向治疗和免疫治疗。IV期肺腺癌病人容易出现其他脏器转移,比如肝转移、脑转移、骨转移和肾上腺转移。总体来说,预后比较差,治愈的机会微乎其微。IV期肺腺癌病人能活多久? 很多病人和家属总会喜欢问“能活多久”这样的问题,实际上,对于个体来说,很难回答具体能活多久,同样的晚期肺腺癌病人,即便同样的治疗方法,效果会千差万别,寿命会差异很大。晚期肺癌病人的生存期与很多因素有关,比如病人的年龄、有没有基础疾病、身体状况怎样、是单发转移还是广泛多脏器转移、有没有进行规范治疗、有没有敏感基因突变、治疗效果如何,这些都决定了不同的病人有不同的生存期。根据第八版肺癌分期对近万例的患者随访结果,IV肺癌病人五年生存率在10%以内,1年生存率为30%-40%,即便在传统放化疗的情况下大部分病人生存期在1-3年。但肺腺癌不同于肺鳞癌的地方是有针对性的靶向药可以选择,所以近十年晚期肺腺癌病人的总体生存期在延长。中国有EGFR突变的肺腺癌人群在50%-55%,这类病人很幸运的能够进行靶向治疗。还有少数肺腺癌病人有ALK基因突变,ROS1基因突变,都可以选择相应的靶向药物。目前,针对EGFR基因的靶向药物大幅度降价,且在医保之内,尤其是一代靶向药吉非替尼,国产仿制药才四百多一盒,还可以报销,这个价格几乎人人能够用得起。在门诊随访的晚期肺腺癌病人中,最长的达到11年,这个病人发现时有骨转移、肝转移,口服易瑞沙后数月病灶就完全消失,肺部残留一些纤维灶,迄今为止这个病人仍不敢停药。其他像口服五六年靶向药的人不在少数。8月31日,国家药品监督管理局批准奥希替尼(泰瑞沙)用于EGFR基因突变型晚期非小细胞肺癌的一线治疗,这是一个具有重大意义的好消息,研究显示,一线使用奥希替尼治疗EGFR阳性肺癌,耐药后使用放化疗等综合治疗方式,病人的中位总生存期是41.4个月,达到了一代靶向药的2倍之多。也就是说,IV期肺腺癌病人使用奥西替尼,一半的病人寿命能达到三年半,这个在传统治疗中是不可想象的。此外,还有针对其他靶点的靶向药和免疫治疗药物在IV期肺腺癌病人中同样发挥了巨大作用,比如新一代ALK抑制剂—阿来替尼(安圣莎)创造了34.8个月无进展生存期的神话,同时还能有效治疗和预防脑转移。KEYNOTE-189试验研究了K药联合化疗治疗晚期非鳞非小细胞肺癌,联合治疗组高达69.2%,而单独化疗组只有49.4%,免疫联合化疗降低了50%的死亡风险。新药、新技术层出不穷,只要有药可用,IV期肺腺癌病人生存时间就可以不断延长。 IV期肺癌大概能活多久?几乎每天都有患者问类似问题。换位思考,完全能理解患者心情。 IV肺癌的预后要看肺癌的病理类型、是否有基因突变、单发转移还是多发转移、是否积极治疗、患者对药物的反应性等很多情况。 比如说,EGFR基因突变的IV期肺腺癌,在十年前平均十个月生存期,因为那个时候没有靶向药物。得益于第一代靶向药物的应用,三年前这部分患者平均生存期达到两年。而现在如果积极治疗,EGFR基因突变的IV肺腺癌平均能有四十个月以上的生存期,因为有第三代靶向药的应用。 ALK基因突变的肺腺癌,现在平均生存期已经在五十个月左右。相信再过三年,又是一个新的进步。 这几年,针对一些少见突变的新药也在陆陆续续被研发,例如NTRK和20插入突变;过去认为无法用靶向药物治疗的KRAS突变,现在也有对应的靶向药物被研发出来。 最后,目前没有任何基因突变的肺癌,也可以接受免疫治疗和化疗。9月10即将公布在世界肺癌大会的数据显示:免疫治疗联合多靶点治疗可以让77%的患者病灶至少缩小30%。 所以,坚持,会有新希望 晚期肺腺癌的生存差异非常大,很难给出一个大概的范围。 一、有EGFR基因突变的患者 这部分患者因为有靶向治疗的机会,所以,一代靶向药物就能把疾病控制1年左右,在出现肿瘤耐药的时候,如果属于耐药基因突变的类型,三代靶向药物能够把病情再控制1年左右,再次出现耐药的情况下,化疗或化疗联合靶向抗血管仍然可以把病情控制半年到1年。 二、有ALK基因突变的患者 这类患者虽然占比较少,但是一旦检测有ALK基因突变,靶向抗ALK的药物能够把晚期患者的生存期大大延长,目前二代靶向抗ALK的药物,最长的观察数据已经达到了7年,仍有部分患者生存。 三、没有敏感基因突变,但PD-L1表达超过50%的患者 这类患者大多没有合适的靶向药物可用,但却是免疫治疗(免疫检查点抑制剂)的适应症,目前一线应用免疫治疗的患者,随访数据刚过5年,但仍有约30%的患者生存。 四、单纯化疗的患者 如果没有靶向抗肿瘤的机会,免疫治疗也疗效欠佳,单纯化疗的患者,生存期基本上在半年到1年。 总之,虽然都是晚期肺腺癌,但生存差异巨大,很难给出一个生存区间预判,需要根据具体患者的具体情况,才能有一个大概的预测。上周国家食药监局刚刚批准奥西替尼泰瑞沙也就是9291为一线用药,在国内特别不抽烟女性肺腺癌患者egfr突变概率很高,根据9291的临床数据显示,其生存期是18个月。也就是说,肺腺癌晚期患者服用第三代靶向药正常情况下的平均生存期是18个月。具体到个人头上肯定是有差距的,我们的病友群里一位上海的病人吃一代超过十年,一位南京的病人吃了六年,刚刚换了9291,个体差异很大的。 至于alk突变,更有钻石突变之说,所谓钻石突变,就是说这种突变概率相对来说很稀有,也说明这种突变生存期超长,临床数据显示一代用克唑替尼是10个月,二代阿来替尼19个月,布加替尼更是达到了26个月,而且三代劳拉替尼也已经上市了。 其次突变概率也较高的ros1靶点用药方案和alk非常接近。 至于其它突变概率更小的靶点比如去年炒的非常火热的ntrk所用的拉罗替尼生存期更长,有效率更高,her2.cmet.ret等也有相应药物,但效果副作用都有差距了。 至于没有突变不能靶向治疗的,如果pd1表达高于五十,经济条件允许,可以尝试免疫疗法,免疫疗法的主要问题是有效率相对低,只有20%左右,如何提高有效率是目前最大的问题,一旦有效,其生存期会比其它治疗方案更乐观,经济条件不允许则只能化疗放疗,化疗大家都知道,副作用大有效率低,这种情况的生存期生存质量也没法和靶向治疗相比了。 总之,肺腺癌的治疗关键在于基因检测,效果如何或者生存期多久看基因突变类型和用药方案,但是就算靶点一样药一样,也同样还存在个体差异。只能说,科学治疗疾病,理性对待病情吧! 肺癌iv期还能活多久?看下真实的临床数据 肺癌四期还能活一年到三年的情况,生存的时间在于肺癌疾病的类型及治疗效果决定的。 如果患者相关检查为中央型肺癌可以采取纤维支气管镜活检病理确诊,如果为周围型肺癌在CT引导下行肺穿刺活检病理确诊,结合病理类型采取化疗、放疗治疗,其次非小细胞肺癌可以采取靶向药物治疗,如果患者治疗效果好的情况下可以活三五年的。 患者都是被一帮无知的饭桶治死的!!!无知至极!!!!给患者 健康 必须只有做到:一排除患者体内毒素垃圾,二增强患者自身免疫力。做不到这两点谈治疗无异于谋财害命。。现在的医疗手段步入了误区,无知的治疗只会雪上加霜,肿瘤是病的源吗?肯定不是。化疗放疗杀癌细胞,不杀好细胞吗??手术化疗只会再一次增加患者体内毒素垃圾,再一次降低免疫力。国家养了一帮无知至极的废物,饭桶!!!
2023-07-24 22:30:071

宝骏LingOS 2.0车机系统发布 率先搭载云朵

易车讯 7月18日,官方发布了宝骏LingOS 2.0车机智能网系统,并宣布云朵成为首款搭载该系统的车型。据悉,LingOS 2.0系统配备全新车规级高算力芯片,超大屏拥有全新UI设计,支持智能语音交互、无缝导航、手机 APP 远程车控等功能。宝骏云朵LingOS 2.0系统配备同级最优车规级高算力芯片——联发科MT8666,采用12纳米工艺芯片制造,最高主频达2.0GHZ,可提供8核算力,搭配6G运行内存及64G存储内存,存储空间大,为车机流畅提供强大的性能保障。宝骏云朵配备15.6英寸超大高清LED屏,结合无实体按键的中控设计,LingOS 2.0打造了全新UI交互系统。车机UI贯彻天空美学的设计理念,色彩灵感来自于天空最美彩云,简洁的布局极具科技感。车机界面提供同级唯一可自定义桌面,用户根据自己的喜好自由调整桌面布局,卡片可随心调整大小、拖动、增减,实现个性化定制。宝骏云朵交互设计采用“L型”极简交互布局,将关键车控集中化布局,集成在中控屏左侧及底部状态栏,整合了自动大灯、空调、Autohold、360影像、导航、门窗等18项功能。此外,宝骏云朵还提供了语音、触屏、方向盘3种方式进行车辆控制,给用户提供丰富多样、自然随心的人机交互方式。宝骏云朵搭载语音交互系统,识别速度低于400ms,唤醒率高达98%,同级最优,能进行20s内的连续对话,地图、切歌、电话等常用功能免唤醒;语音系统还支持主副驾分区识别功能,实现互不干扰的语音交流。此外,车机导航内置高德地图,实现手机车机账户互通,导航信息自动同步至车机;高德地图、微信、美团、大众点评等应用软件支持位置分享,导航系统具备智能出行提醒功能。打开易车 App,搜索“真十万公里长测”,看最真实的车辆长测报告。
2023-07-24 22:30:061

Smith&Nephew为什么叫 施乐辉?名字的意思是什么?

老Smith是创办人,他的侄子后来加入并继承所以叫史密斯和他侄子。
2023-07-24 22:30:041

杜甫的望岳的解释

木有钱U0001f4b0
2023-07-24 22:30:024

honey是什么意思中文翻译

  honey表达的意思有很多种,那么你知道honey做动词,名词和形容词分别都有哪些意思吗?下面我为大家带来honey的英语意思解释和英语例句,欢迎大家一起学习!   honey作名词的意思:   蜂蜜;<口>宝贝;可爱的人   honey作动词的意思:   给u2026加蜜;对u2026甜言蜜语   honey作形容词的意思:   蜜的;心爱的;加了蜜的   honey的英语音标:   英 [u02c8hu028cni] 美 [u02c8hu028cni]   honey的时态:   现在分词: honeying   过去式: honeyed   过去分词: honeyed   honey的英语例句:   1. Add more honey if you have a sweet tooth.   如果你喜欢吃甜的就多加点蜂蜜。   2. Now don"t talk so loud and bother him, honey.   亲爱的,好了,别这么大声说话打扰他。   3. Sweeten dishes sparingly with honey, or con-centrated apple or pear juice.   加一点蜂蜜或浓缩苹果汁或梨汁,让菜带点甜味。   4. The Australians fry their bananas and sweeten them with honey.   澳大利亚人把香蕉炸了,然后再淋上蜂蜜吃。   5. Add honey to counterbalance the acidity.   加点蜂蜜来调和酸味。   6. Warm the honey until it becomes runny.   将蜂蜜加热直到它变稀。   7. Honey can help to detox the body.   蜂蜜能帮助身体解毒。   8. "You want more?" roared Claire. "Forget it, honey."   “你还想要?”克莱尔吼道。“想都别想,宝贝。”   9. I opened by saying, "Honey, you look sensational."   我第一句话是,“宝贝,你看起来真是美极了。”   10. Whip the eggs, oils and honey together.   把鸡蛋、油和蜂蜜搅打在一起。   11. Honey is a naturally acidic substance.   蜂蜜是天然的酸性物质。   12. Have you seen my keys, honey?   你见到我的钥匙了吗,宝贝?   13. That new car of his is a real honey!   他的那辆新汽车真是棒极了!   14. Honey peaches are in now and we can eat them every day.   现在水蜜桃正上市,我们每天都可以吃到.   15. A scent of honey wafted up from the hives.   一股蜂蜜的香味从蜂房里飘上来.
2023-07-24 22:29:571